Frequent urination after Bedinvetmab (Librela) in dogs

The FDA has received 225 reports of frequent urination in dogs after Bedinvetmab. That is 1.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

225Reports

64%Marked serious

8.0%Recovered

15%Died or euthanised

9 daysTypical onset

How soon it started

Same day

45 23%

1–2 days

22 11%

3–7 days

31 16%

1–4 weeks

49 25%

Over a month

52 26%

How the animals did

Recovered

17 7.6%

Recovered with lasting effects

1 0.4%

Still unwell when reported

138 61%

Died

12 5.3%

Euthanised

22 9.8%

Not known

35 16%

Problems reported at the same time

Urinary tract infection

62 28%

Inappropriate urination

56 25%

45 20%

44 20%

41 18%

37 16%

33 15%

30 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

136

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause frequent urination in dogs?: 225 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Frequent urination with similar medicines

Frequent urination after Lokivetmab (Cytopoint) 24 reports · 0.4% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with frequent urination