Difficulty to rise after Bedinvetmab (Librela) in dogs

The FDA has received 339 reports of difficulty to rise in dogs after Bedinvetmab. That is 1.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

339Reports

66%Marked serious

5.6%Recovered

28%Died or euthanised

7 daysTypical onset

How soon it started

Same day

50 18%

1–2 days

59 21%

3–7 days

39 14%

1–4 weeks

40 14%

Over a month

90 32%

How the animals did

Recovered

19 5.6%

Still unwell when reported

194 57%

Died

22 6.5%

Euthanised

74 22%

Not known

30 8.8%

Problems reported at the same time

122 36%

96 28%

96 28%

80 24%

67 20%

Proprioception deficit

50 15%

Breathing problems

45 13%

Walking difficulty

42 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

142

12+ years

170

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause difficulty to rise in dogs?: 339 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with difficulty to rise