Cognitive disorder after Bedinvetmab (Librela) in dogs

142 reports to the FDA describe cognitive disorder in dogs given Bedinvetmab. That is 0.7% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

142Reports

73%Marked serious

7.7%Recovered

34%Died or euthanised

4 daysTypical onset

How soon it started

Same day

42 33%

1–2 days

13 10%

3–7 days

20 16%

1–4 weeks

17 13%

Over a month

35 28%

How the animals did

Recovered

11 7.7%

Still unwell when reported

54 38%

Died

10 7.0%

Euthanised

38 27%

Not known

29 20%

Problems reported at the same time

48 34%

30 21%

29 20%

28 20%

27 19%

26 18%

26 18%

25 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause cognitive disorder in dogs?: 142 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with cognitive disorder