Abnormal movement after Bedinvetmab (Librela) in dogs

The FDA has received 84 reports of abnormal movement in dogs after Bedinvetmab. That is 0.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

84Reports
76%Marked serious
19%Recovered
37%Died or euthanised
13 daysTypical onset
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How soon it started

Same day
12 16%
1–2 days
8 11%
3–7 days
12 16%
1–4 weeks
20 27%
Over a month
21 29%

How the animals did

Recovered
16 19%
Still unwell when reported
31 37%
Died
9 11%
Euthanised
22 26%
Not known
6 7.1%

Problems reported at the same time

Death
31 37%
Loss of appetite
23 27%
Seizures
21 25%
Weakness
21 25%
Wobbliness (ataxia)
19 23%
Behaviour change
18 21%
Breathing problems
17 20%
Vomiting
16 19%

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
4
8–11 years
34
12+ years
45

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause abnormal movement in dogs?
84 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 13 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with abnormal movement