Hypoglycaemia after Velagliflozin (Senvelgo) in cats

The FDA has received 144 reports of hypoglycaemia in cats after Velagliflozin. That is 3.0% of all reports for this medicine, compared with 1.1% across reports for all cat medicines, so it is reported unusually often with this medicine.

144Reports
51%Marked serious
14%Recovered
19%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
9 6.7%
1–2 days
27 20%
3–7 days
38 28%
1–4 weeks
30 22%
Over a month
30 22%

How the animals did

Recovered
20 14%
Still unwell when reported
16 11%
Died
5 3.5%
Euthanised
23 16%
Not known
80 56%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
1
4–7 years
23
8–11 years
56
12+ years
53

About this medicine

Velagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Senvelgo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Velagliflozin cause hypoglycaemia in cats?
144 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoglycaemia with similar medicines

All reported side effects of Velagliflozin in cats · Medicines most reported with hypoglycaemia