Unrelated death after Tiletamine + Zolazepam in cats

25 reports to the FDA describe unrelated death in cats given Tiletamine + Zolazepam. That is 1.5% of all reports for this medicine, compared with 0.1% across reports for all cat medicines, so it is reported unusually often with this medicine.

25Reports

100%Marked serious

0.0%Recovered

100%Died or euthanised

Same dayTypical onset

How soon it started

Same day

22 96%

1–2 days

1 4.3%

3–7 days

0 0.0%

1–4 weeks

0 0.0%

Over a month

0 0.0%

How the animals did

Euthanised

25 100%

Problems reported at the same time

Didn't work as expected

21 84%

Death

6 24%

Behaviour change

3 12%

Pain

1 4.0%

Immediate pain upon injection

1 4.0%

Vocalising

1 4.0%

Central nervous system disorder

1 4.0%

Hypotension

1 4.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Tiletamine + Zolazepam cause unrelated death in cats?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Tiletamine + Zolazepam in cats · Medicines most reported with unrelated death