Death after Tiletamine + Zolazepam in cats

525 reports to the FDA describe death in cats given Tiletamine + Zolazepam. That is 32% of all reports for this medicine, compared with 8.9% across reports for all cat medicines, so it is reported unusually often with this medicine.

525Reports
36%Marked serious
0.0%Recovered
99%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
146 82%
1–2 days
15 8.4%
3–7 days
9 5.0%
1–4 weeks
4 2.2%
Over a month
5 2.8%

How the animals did

Died
486 93%
Euthanised
33 6.3%
Not known
6 1.1%

Problems reported at the same time

Age of the animals

Under 1 year
205
1–3 years
105
4–7 years
53
8–11 years
31
12+ years
21

About this medicine

Type: medicine.

Questions owners ask

Can Tiletamine + Zolazepam cause death in cats?
525 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

All reported side effects of Tiletamine + Zolazepam in cats · Medicines most reported with death