Apnoea after Tiletamine + Zolazepam in cats

152 reports to the FDA describe apnoea in cats given Tiletamine + Zolazepam. That is 9.2% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

152Reports
11%Marked serious
4.6%Recovered
68%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
19 95%
1–2 days
0 0.0%
3–7 days
0 0.0%
1–4 weeks
1 5.0%
Over a month
0 0.0%

How the animals did

Recovered
7 4.6%
Still unwell when reported
1 0.7%
Died
104 68%
Not known
40 26%

Problems reported at the same time

Age of the animals

Under 1 year
61
1–3 years
35
4–7 years
17
8–11 years
7
12+ years
6

About this medicine

Type: medicine.

Questions owners ask

Can Tiletamine + Zolazepam cause apnoea in cats?
152 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Apnoea with similar medicines

All reported side effects of Tiletamine + Zolazepam in cats · Medicines most reported with apnoea