Hypothermia after Tiletamine + Zolazepam in cats

77 reports to the FDA describe hypothermia in cats given Tiletamine + Zolazepam. That is 4.6% of all reports for this medicine, compared with 1.2% across reports for all cat medicines, so it is reported unusually often with this medicine.

77Reports
30%Marked serious
17%Recovered
29%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
19 61%
1–2 days
4 13%
3–7 days
2 6.5%
1–4 weeks
4 13%
Over a month
2 6.5%

How the animals did

Recovered
13 17%
Still unwell when reported
9 12%
Died
20 26%
Euthanised
2 2.6%
Not known
33 43%

Problems reported at the same time

Age of the animals

Under 1 year
24
1–3 years
11
4–7 years
8
8–11 years
10
12+ years
15

About this medicine

Type: medicine.

Questions owners ask

Can Tiletamine + Zolazepam cause hypothermia in cats?
77 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypothermia with similar medicines

All reported side effects of Tiletamine + Zolazepam in cats · Medicines most reported with hypothermia