Sedation prolonged after Tiletamine + Zolazepam in cats

The FDA has received 30 reports of sedation prolonged in cats after Tiletamine + Zolazepam. That is 1.8% of all reports for this medicine, compared with 0.2% across reports for all cat medicines, so it is reported unusually often with this medicine.

30Reports
37%Marked serious
17%Recovered
20%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
18 100%
1–2 days
0 0.0%
3–7 days
0 0.0%
1–4 weeks
0 0.0%
Over a month
0 0.0%

How the animals did

Recovered
5 17%
Still unwell when reported
10 33%
Died
3 10%
Euthanised
3 10%
Not known
9 30%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
5
4–7 years
4
8–11 years
4
12+ years
8

About this medicine

Type: medicine.

Questions owners ask

Can Tiletamine + Zolazepam cause sedation prolonged in cats?
30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Sedation prolonged with similar medicines

All reported side effects of Tiletamine + Zolazepam in cats · Medicines most reported with sedation prolonged