No sign after Spinosad (Comfortis) in cats

The FDA has received 28 reports of no sign in cats after Spinosad. That is 0.2% of all reports for this medicine, compared with 0.9% across reports for all cat medicines, so it is reported less often than average with this medicine.

28Reports

7.1%Marked serious

7.1%Recovered

3.6%Died or euthanised

–Typical onset

How the animals did

Recovered

2 7.1%

Died

1 3.6%

Not known

25 89%

Problems reported at the same time

25 89%

2 7.1%

2 7.1%

1 3.6%

1 3.6%

1 3.6%

1 3.6%

1 3.6%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Spinosad kills fleas; monthly chewable.

Products with this ingredient include Comfortis. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Spinosad cause no sign in cats?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

No sign with similar medicines

No sign after Imidacloprid + Moxidectin (Advantage Multi) 27 reports · 0.3% of its reports
No sign after Flumethrin + Imidacloprid (Seresto) 20 reports · 3.0% of its reports

All reported side effects of Spinosad in cats · Medicines most reported with no sign