Hiding after Selamectin (Revolution) in cats

362 reports to the FDA describe hiding in cats given Selamectin. That is 1.6% of all reports for this medicine, compared with 2.4% across reports for all cat medicines.

362Reports
12%Marked serious
9.7%Recovered
8.8%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
84 49%
1–2 days
41 24%
3–7 days
21 12%
1–4 weeks
14 8.2%
Over a month
10 5.9%

How the animals did

Recovered
35 9.7%
Still unwell when reported
73 20%
Died
23 6.4%
Euthanised
9 2.5%
Not known
222 61%

Problems reported at the same time

Age of the animals

Under 1 year
26
1–3 years
124
4–7 years
83
8–11 years
73
12+ years
41

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause hiding in cats?
362 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hiding with similar medicines

All reported side effects of Selamectin in cats · Medicines most reported with hiding