Cough after Selamectin (Revolution) in cats

108 reports to the FDA describe cough in cats given Selamectin. That is 0.5% of all reports for this medicine, compared with 0.4% across reports for all cat medicines.

108Reports
16%Marked serious
10%Recovered
19%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
9 29%
1–2 days
10 32%
3–7 days
8 26%
1–4 weeks
2 6.5%
Over a month
2 6.5%

How the animals did

Recovered
11 10%
Still unwell when reported
16 15%
Died
18 17%
Euthanised
3 2.8%
Not known
60 56%

Problems reported at the same time

Age of the animals

Under 1 year
21
1–3 years
31
4–7 years
24
8–11 years
13
12+ years
14

About this medicine

Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this ingredient include Revolution. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Selamectin cause cough in cats?
108 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Selamectin in cats · Medicines most reported with cough