Accidental exposure after Sarolaner (Simparica) in cats

92 reports to the FDA describe accidental exposure in cats given Sarolaner. That is 36% of all reports for this medicine, compared with 2.6% across reports for all cat medicines, so it is reported unusually often with this medicine.

92Reports
62%Marked serious
18%Recovered
5.4%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
64 71%
1–2 days
20 22%
3–7 days
2 2.2%
1–4 weeks
2 2.2%
Over a month
2 2.2%

How the animals did

Recovered
17 18%
Still unwell when reported
59 64%
Died
2 2.2%
Euthanised
3 3.3%
Not known
11 12%

Problems reported at the same time

Age of the animals

Under 1 year
25
1–3 years
21
4–7 years
14
8–11 years
10
12+ years
13

About this medicine

Sarolaner kills fleas, ticks and some mites; monthly.

Products with this ingredient include Simparica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Sarolaner cause accidental exposure in cats?
92 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Accidental exposure with similar medicines

All reported side effects of Sarolaner in cats · Medicines most reported with accidental exposure