Didn't stop mites after Sarolaner + Selamectin (Revolution Plus) in cats

117 reports to the FDA describe didn't stop mites in cats given Sarolaner + Selamectin. That is 1.4% of all reports for this medicine, compared with 1.0% across reports for all cat medicines.

117Reports
33%Marked serious
0.9%Recovered
0.0%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
28 31%
1–2 days
1 1.1%
3–7 days
4 4.5%
1–4 weeks
30 34%
Over a month
26 29%

How the animals did

Recovered
1 0.9%
Still unwell when reported
54 46%
Not known
62 53%

Problems reported at the same time

2 1.7%
2 1.7%
Immediate pain upon application
1 0.9%
1 0.9%

Age of the animals

Under 1 year
26
1–3 years
21
4–7 years
11
8–11 years
17
12+ years
3

About this medicine

Sarolaner kills fleas, ticks and some mites; monthly. Selamectin prevents heartworm and treats fleas, ear mites and some worms (spot-on).

Products with this combination include Revolution Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Sarolaner + Selamectin cause didn't stop mites in cats?
117 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't stop mites with similar medicines

All reported side effects of Sarolaner + Selamectin in cats · Medicines most reported with didn't stop mites