Accidental exposure after Milbemycin Oxime (Interceptor) in cats
The FDA has received 36 reports of accidental exposure in cats after Milbemycin Oxime. That is 8.9% of all reports for this medicine, compared with 2.6% across reports for all cat medicines, so it is reported unusually often with this medicine.
36Reports
2.8%Marked serious
2.8%Recovered
2.8%Died or euthanised
–Typical onset
Sponsored
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Milbemycin Oxime prevents heartworm and controls some intestinal worms (monthly).
Products with this ingredient include Interceptor. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Milbemycin Oxime cause accidental exposure in cats?
- 36 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Accidental exposure with similar medicines
- Accidental exposure after Selamectin (Revolution) 352 reports · 1.6% of its reports
- Accidental exposure after Eprinomectin + Esafoxolaner + Praziquantel (NexGard Combo) 153 reports · 4.7% of its reports
- Accidental exposure after Ivermectin (Heartgard) 53 reports · 5.5% of its reports
- Accidental exposure after Milbemycin Oxime + Spinosad (Trifexis) 96 reports · 32% of its reports
- Accidental exposure after Ivermectin + Pyrantel (Heartgard Plus) 37 reports · 56% of its reports
All reported side effects of Milbemycin Oxime in cats · Medicines most reported with accidental exposure