Not sleeping after Midazolam in cats

The FDA has received 43 reports of not sleeping in cats after Midazolam. That is 5.7% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

43Reports

12%Marked serious

37%Recovered

2.3%Died or euthanised

Same dayTypical onset

How soon it started

Same day

30 70%

1–2 days

9 21%

3–7 days

1 2.3%

1–4 weeks

1 2.3%

Over a month

2 4.7%

How the animals did

Recovered

16 37%

Still unwell when reported

19 44%

Euthanised

1 2.3%

Not known

7 16%

Problems reported at the same time

Restlessness or agitation

30 70%

15 35%

13 30%

9 21%

7 16%

6 14%

Staring

6 14%

Pacing

6 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause not sleeping in cats?: 43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not sleeping with similar medicines

Not sleeping after Ketamine 52 reports · 1.6% of its reports
Not sleeping after Butorphanol 49 reports · 2.2% of its reports
Not sleeping after Isoflurane 85 reports · 4.2% of its reports
Not sleeping after Propofol 55 reports · 4.7% of its reports
Not sleeping after Atipamezole 20 reports · 1.9% of its reports

All reported side effects of Midazolam in cats · Medicines most reported with not sleeping