Not sleeping after Propofol in cats

The FDA has received 55 reports of not sleeping in cats after Propofol. That is 4.7% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

55Reports

18%Marked serious

36%Recovered

3.6%Died or euthanised

Same dayTypical onset

How soon it started

Same day

37 69%

1–2 days

14 26%

3–7 days

1 1.9%

1–4 weeks

0 0.0%

Over a month

2 3.7%

How the animals did

Recovered

20 36%

Still unwell when reported

23 42%

Died

1 1.8%

Euthanised

1 1.8%

Not known

10 18%

Problems reported at the same time

Restlessness or agitation

34 62%

25 45%

18 33%

14 25%

10 18%

9 16%

9 16%

9 16%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause not sleeping in cats?: 55 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not sleeping with similar medicines

Not sleeping after Ketamine 52 reports · 1.6% of its reports
Not sleeping after Butorphanol 49 reports · 2.2% of its reports
Not sleeping after Isoflurane 85 reports · 4.2% of its reports
Not sleeping after Atipamezole 20 reports · 1.9% of its reports
Not sleeping after Midazolam 43 reports · 5.7% of its reports

All reported side effects of Propofol in cats · Medicines most reported with not sleeping