Behaviour change after Midazolam in cats

The FDA has received 110 reports of behaviour change in cats after Midazolam. That is 15% of all reports for this medicine, compared with 5.4% across reports for all cat medicines, so it is reported unusually often with this medicine.

110Reports
50%Marked serious
24%Recovered
13%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
65 60%
1–2 days
23 21%
3–7 days
10 9.3%
1–4 weeks
6 5.6%
Over a month
4 3.7%

How the animals did

Recovered
26 24%
Still unwell when reported
45 41%
Died
6 5.5%
Euthanised
8 7.3%
Not known
25 23%

Problems reported at the same time

Age of the animals

Under 1 year
22
1–3 years
12
4–7 years
26
8–11 years
19
12+ years
27

About this medicine

Type: medicine.

Questions owners ask

Can Midazolam cause behaviour change in cats?
110 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Midazolam in cats · Medicines most reported with behaviour change