Unresponsive after Isoflurane in cats

The FDA has received 41 reports of unresponsive in cats after Isoflurane. That is 2.0% of all reports for this medicine, compared with 0.6% across reports for all cat medicines, so it is reported unusually often with this medicine.

41Reports

83%Marked serious

2.4%Recovered

54%Died or euthanised

Same dayTypical onset

How soon it started

Same day

21 58%

1–2 days

9 25%

3–7 days

1 2.8%

1–4 weeks

3 8.3%

Over a month

2 5.6%

How the animals did

Recovered

1 2.4%

Still unwell when reported

10 24%

Died

12 29%

Euthanised

10 24%

Not known

8 20%

Problems reported at the same time

22 54%

12 29%

10 24%

10 24%

10 24%

8 20%

8 20%

8 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause unresponsive in cats?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Unresponsive with similar medicines

Unresponsive after Ketamine 56 reports · 1.7% of its reports
Unresponsive after Butorphanol 45 reports · 2.0% of its reports
Unresponsive after Tiletamine + Zolazepam 21 reports · 1.3% of its reports
Unresponsive after Methylprednisolone 23 reports · 1.4% of its reports
Unresponsive after Propofol 32 reports · 2.7% of its reports
Unresponsive after Midazolam 24 reports · 3.2% of its reports

All reported side effects of Isoflurane in cats · Medicines most reported with unresponsive