Liver problems after Imidacloprid + Moxidectin (Advantage Multi) in cats
69 reports to the FDA describe liver problems in cats given Imidacloprid + Moxidectin. That is 0.8% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported less often than average with this medicine.
69Reports
72%Marked serious
13%Recovered
30%Died or euthanised
1 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Imidacloprid kills fleas (spot-on or collar). Moxidectin prevents heartworm disease (monthly topical, or a 6- or 12-month injection for dogs).
Products with this combination include Advantage Multi. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Imidacloprid + Moxidectin cause liver problems in cats?
- 69 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 1 day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Liver problems with similar medicines
- Liver problems after Spinosad (Comfortis) 97 reports · 0.8% of its reports
- Liver problems after Nitenpyram (Capstar) 44 reports · 0.5% of its reports
- Liver problems after Lufenuron 36 reports · 3.2% of its reports
All reported side effects of Imidacloprid + Moxidectin in cats · Medicines most reported with liver problems