Loss of appetite after Fipronil + S-methoprene (Frontline Plus) in cats
The FDA has received 29 reports of loss of appetite in cats after Fipronil + S-methoprene. That is 7.9% of all reports for this medicine, compared with 14% across reports for all cat medicines, so it is reported less often than average with this medicine.
29Reports
48%Marked serious
24%Recovered
24%Died or euthanised
4 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Fipronil kills fleas and ticks (spot-on).
Products with this combination include Frontline Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Fipronil + S-methoprene cause loss of appetite in cats?
- 29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 4 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Loss of appetite with similar medicines
- Loss of appetite after Spinosad (Comfortis) 632 reports · 5.5% of its reports
- Loss of appetite after Nitenpyram (Capstar) 573 reports · 6.6% of its reports
- Loss of appetite after Imidacloprid + Moxidectin (Advantage Multi) 901 reports · 11% of its reports
- Loss of appetite after Lufenuron 207 reports · 19% of its reports
- Loss of appetite after Flumethrin + Imidacloprid (Seresto) 58 reports · 8.6% of its reports
- Loss of appetite after Imidacloprid + Pyriproxyfen 54 reports · 8.2% of its reports
- Loss of appetite after Fipronil 37 reports · 7.4% of its reports
- Loss of appetite after Imidacloprid 24 reports · 9.5% of its reports
All reported side effects of Fipronil + S-methoprene in cats · Medicines most reported with loss of appetite