Lethargy after Fipronil + S-methoprene (Frontline Plus) in cats
51 reports to the FDA describe lethargy in cats given Fipronil + S-methoprene. That is 14% of all reports for this medicine, compared with 14% across reports for all cat medicines.
51Reports
55%Marked serious
33%Recovered
25%Died or euthanised
5 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Fipronil kills fleas and ticks (spot-on).
Products with this combination include Frontline Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Fipronil + S-methoprene cause lethargy in cats?
- 51 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 5 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Lethargy with similar medicines
- Lethargy after Spinosad (Comfortis) 1,080 reports · 9.3% of its reports
- Lethargy after Nitenpyram (Capstar) 926 reports · 11% of its reports
- Lethargy after Imidacloprid + Moxidectin (Advantage Multi) 1,394 reports · 17% of its reports
- Lethargy after Lufenuron 236 reports · 21% of its reports
- Lethargy after Flumethrin + Imidacloprid (Seresto) 72 reports · 11% of its reports
- Lethargy after Imidacloprid + Pyriproxyfen 73 reports · 11% of its reports
- Lethargy after Fipronil 62 reports · 12% of its reports
- Lethargy after Imidacloprid 33 reports · 13% of its reports
All reported side effects of Fipronil + S-methoprene in cats · Medicines most reported with lethargy