Allergic reaction after Dexmedetomidine (Dexdomitor) in cats

36 reports to the FDA describe allergic reaction in cats given Dexmedetomidine. That is 1.4% of all reports for this medicine, compared with 0.9% across reports for all cat medicines, so it is reported unusually often with this medicine.

36Reports
81%Marked serious
44%Recovered
19%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
31 89%
1–2 days
4 11%
3–7 days
0 0.0%
1–4 weeks
0 0.0%
Over a month
0 0.0%

How the animals did

Recovered
16 44%
Still unwell when reported
11 31%
Died
7 19%
Not known
2 5.6%

Problems reported at the same time

Breathing problems
11 31%
Swelling
10 28%
Drooling
9 25%
Death
7 19%
Pale mucous membrane
5 14%
Hypothermia
5 14%
Fever
4 11%
Behaviour change
4 11%

Age of the animals

Under 1 year
11
1–3 years
5
4–7 years
4
8–11 years
8
12+ years
5

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause allergic reaction in cats?
36 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Allergic reaction with similar medicines

All reported side effects of Dexmedetomidine in cats · Medicines most reported with allergic reaction