Allergic reaction after Buprenorphine in cats

The FDA has received 56 reports of allergic reaction in cats after Buprenorphine. That is 1.0% of all reports for this medicine, compared with 0.9% across reports for all cat medicines.

56Reports

61%Marked serious

46%Recovered

20%Died or euthanised

Same dayTypical onset

How soon it started

Same day

39 72%

1–2 days

9 17%

3–7 days

1 1.9%

1–4 weeks

2 3.7%

Over a month

3 5.6%

How the animals did

Recovered

25 45%

Recovered with lasting effects

1 1.8%

Still unwell when reported

14 25%

Died

10 18%

Euthanised

1 1.8%

Not known

5 8.9%

Problems reported at the same time

Swelling

17 30%

Restlessness or agitation

11 20%

11 20%

11 20%

10 18%

8 14%

8 14%

8 14%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause allergic reaction in cats?: 56 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Allergic reaction with similar medicines

Allergic reaction after Dexmedetomidine (Dexdomitor) 36 reports · 1.4% of its reports

All reported side effects of Buprenorphine in cats · Medicines most reported with allergic reaction