Buprenorphine side effects in cats

5,599 reports sent to the FDA between 2006 and 2026 involve Buprenorphine in cats. The most reported problems were loss of appetite, behaviour change, restlessness or agitation. 34% were marked serious, and where it was recorded, signs eased after stopping the medicine in 53% of cases.

5,599Reports
34%Marked serious
28%Only medicine involved
29%Recovered
14%Died or euthanised
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About this medicine

Buprenorphine pain relief (an opioid).

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
9 0.2%
Didn't stop ticks
2 0.0%
Didn't stop worms
2 0.0%
Didn't prevent heartworm
2 0.0%

How soon problems started

Same day
2,742 53%
1–2 days
1,294 25%
3–7 days
491 9.5%
1–4 weeks
375 7.3%
Over a month
250 4.9%

Time from the first dose to the first sign, where both dates were reported (5,152 reports).

How the animals did

Recovered
1,639 29%
Recovered with lasting effects
10 0.2%
Still unwell when reported
1,759 31%
Died
462 8.3%
Euthanised
300 5.4%
Not known
1,429 26%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other sedative or anaesthetics for cats