Not sleeping after Buprenorphine in cats

372 reports to the FDA describe not sleeping in cats given Buprenorphine. That is 6.6% of all reports for this medicine, compared with 0.3% across reports for all cat medicines, so it is reported unusually often with this medicine.

372Reports

14%Marked serious

33%Recovered

4.6%Died or euthanised

Same dayTypical onset

How soon it started

Same day

240 67%

1–2 days

82 23%

3–7 days

11 3.1%

1–4 weeks

11 3.1%

Over a month

13 3.6%

How the animals did

Recovered

123 33%

Still unwell when reported

138 37%

Died

7 1.9%

Euthanised

10 2.7%

Not known

94 25%

Problems reported at the same time

Restlessness or agitation

211 57%

158 42%

133 36%

114 31%

65 17%

59 16%

57 15%

50 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

103

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause not sleeping in cats?: 372 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Not sleeping with similar medicines

Not sleeping after Dexmedetomidine (Dexdomitor) 64 reports · 2.4% of its reports

All reported side effects of Buprenorphine in cats · Medicines most reported with not sleeping