Didn't work as expected after Buprenorphine in cats

The FDA has received 245 reports of didn't work as expected in cats after Buprenorphine. That is 4.4% of all reports for this medicine, compared with 8.7% across reports for all cat medicines, so it is reported less often than average with this medicine.

245Reports

39%Marked serious

16%Recovered

15%Died or euthanised

2 daysTypical onset

How soon it started

Same day

72 33%

1–2 days

48 22%

3–7 days

37 17%

1–4 weeks

35 16%

Over a month

23 11%

How the animals did

Recovered

39 16%

Still unwell when reported

82 33%

Died

13 5.3%

Euthanised

24 9.8%

Not known

87 36%

Problems reported at the same time

68 28%

38 16%

36 15%

29 12%

21 8.6%

17 6.9%

17 6.9%

17 6.9%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause didn't work as expected in cats?: 245 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Dexmedetomidine (Dexdomitor) 476 reports · 18% of its reports

All reported side effects of Buprenorphine in cats · Medicines most reported with didn't work as expected