Liver problems after Cyclosporine (Atopica) in cats

145 reports to the FDA describe liver problems in cats given Cyclosporine. That is 4.8% of all reports for this medicine, compared with 2.8% across reports for all cat medicines, so it is reported unusually often with this medicine.

145Reports

61%Marked serious

10%Recovered

39%Died or euthanised

36 daysTypical onset

How soon it started

Same day

10 11%

1–2 days

3 3.3%

3–7 days

5 5.6%

1–4 weeks

22 24%

Over a month

50 56%

How the animals did

Recovered

15 10%

Still unwell when reported

34 23%

Died

27 19%

Euthanised

30 21%

Not known

39 27%

Problems reported at the same time

85 59%

75 52%

56 39%

48 33%

43 30%

33 23%

30 21%

28 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause liver problems in cats?: 145 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 36 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

Liver problems after Oclacitinib (Apoquel) 71 reports · 15% of its reports

All reported side effects of Cyclosporine in cats · Medicines most reported with liver problems