Lethargy after Cyclosporine (Atopica) in cats

The FDA has received 350 reports of lethargy in cats after Cyclosporine. That is 12% of all reports for this medicine, compared with 14% across reports for all cat medicines.

350Reports

49%Marked serious

27%Recovered

21%Died or euthanised

10 daysTypical onset

How soon it started

Same day

65 27%

1–2 days

29 12%

3–7 days

20 8.4%

1–4 weeks

46 19%

Over a month

77 32%

How the animals did

Recovered

95 27%

Recovered with lasting effects

1 0.3%

Still unwell when reported

89 25%

Died

29 8.3%

Euthanised

46 13%

Not known

90 26%

Problems reported at the same time

195 56%

112 32%

103 29%

72 21%

51 15%

48 14%

42 12%

38 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

100

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause lethargy in cats?: 350 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lethargy with similar medicines

Lethargy after Oclacitinib (Apoquel) 93 reports · 20% of its reports

All reported side effects of Cyclosporine in cats · Medicines most reported with lethargy