Loss of appetite after Butorphanol + Dexmedetomidine + Ketamine in cats

29 reports to the FDA describe loss of appetite in cats given Butorphanol + Dexmedetomidine + Ketamine. That is 23% of all reports for this medicine, compared with 14% across reports for all cat medicines, so it is reported unusually often with this medicine.

29Reports
52%Marked serious
21%Recovered
24%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
9 32%
1–2 days
11 39%
3–7 days
3 11%
1–4 weeks
1 3.6%
Over a month
4 14%

How the animals did

Recovered
6 21%
Still unwell when reported
11 38%
Died
5 17%
Euthanised
2 6.9%
Not known
5 17%

Problems reported at the same time

Lethargy
9 31%
Dilated pupils
7 24%
Death
7 24%
Weight loss
6 21%
Not drinking
6 21%
Kidney problems
5 17%

Age of the animals

Under 1 year
7
1–3 years
2
4–7 years
7
8–11 years
4
12+ years
9

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Questions owners ask

Can Butorphanol + Dexmedetomidine + Ketamine cause loss of appetite in cats?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Butorphanol + Dexmedetomidine + Ketamine in cats · Medicines most reported with loss of appetite