Not himself/herself after Buprenorphine in cats

82 reports to the FDA describe not himself/herself in cats given Buprenorphine. That is 1.5% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

82Reports

40%Marked serious

20%Recovered

13%Died or euthanised

Same dayTypical onset

How soon it started

Same day

42 52%

1–2 days

18 22%

3–7 days

6 7.4%

1–4 weeks

8 9.9%

Over a month

7 8.6%

How the animals did

Recovered

16 20%

Still unwell when reported

32 39%

Died

7 8.5%

Euthanised

4 4.9%

Not known

23 28%

Problems reported at the same time

Loss of appetite

39 48%

Restlessness or agitation

30 37%

30 37%

24 29%

18 22%

16 20%

15 18%

12 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause not himself/herself in cats?: 82 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Buprenorphine in cats · Medicines most reported with not himself/herself