Neutrophilia after Buprenorphine in cats

74 reports to the FDA describe neutrophilia in cats given Buprenorphine. That is 1.3% of all reports for this medicine, compared with 0.7% across reports for all cat medicines, so it is reported unusually often with this medicine.

74Reports

77%Marked serious

22%Recovered

28%Died or euthanised

1 daysTypical onset

How soon it started

Same day

27 40%

1–2 days

14 21%

3–7 days

10 15%

1–4 weeks

6 9.0%

Over a month

10 15%

How the animals did

Recovered

15 20%

Recovered with lasting effects

1 1.4%

Still unwell when reported

27 36%

Died

2 2.7%

Euthanised

19 26%

Not known

10 14%

Problems reported at the same time

54 73%

39 53%

37 50%

28 38%

27 36%

24 32%

23 31%

23 31%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause neutrophilia in cats?: 74 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

Neutrophilia after Dexmedetomidine (Dexdomitor) 23 reports · 0.9% of its reports

All reported side effects of Buprenorphine in cats · Medicines most reported with neutrophilia