Leucocytosis after Buprenorphine in cats

64 reports to the FDA describe leucocytosis in cats given Buprenorphine. That is 1.1% of all reports for this medicine, compared with 0.9% across reports for all cat medicines.

64Reports

73%Marked serious

17%Recovered

25%Died or euthanised

1 daysTypical onset

How soon it started

Same day

20 34%

1–2 days

20 34%

3–7 days

10 17%

1–4 weeks

3 5.1%

Over a month

6 10%

How the animals did

Recovered

10 16%

Recovered with lasting effects

1 1.6%

Still unwell when reported

27 42%

Died

7 11%

Euthanised

9 14%

Not known

10 16%

Problems reported at the same time

38 59%

33 52%

30 47%

27 42%

25 39%

20 31%

18 28%

16 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause leucocytosis in cats?: 64 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

Leucocytosis after Dexmedetomidine (Dexdomitor) 23 reports · 0.9% of its reports

All reported side effects of Buprenorphine in cats · Medicines most reported with leucocytosis