Injection site reaction after Buprenorphine in cats

84 reports to the FDA describe injection site reaction in cats given Buprenorphine. That is 1.5% of all reports for this medicine, compared with 1.2% across reports for all cat medicines.

84Reports

63%Marked serious

15%Recovered

13%Died or euthanised

7 daysTypical onset

How soon it started

Same day

11 19%

1–2 days

13 22%

3–7 days

6 10%

1–4 weeks

22 37%

Over a month

7 12%

How the animals did

Recovered

11 13%

Recovered with lasting effects

2 2.4%

Still unwell when reported

42 50%

Died

4 4.8%

Euthanised

7 8.3%

Not known

18 21%

Problems reported at the same time

Loss of appetite

23 27%

Lethargy

16 19%

Limb amputation

15 18%

Abnormal radiograph finding

13 15%

11 13%

11 13%

10 12%

10 12%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause injection site reaction in cats?: 84 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Dexmedetomidine (Dexdomitor) 52 reports · 2.0% of its reports

All reported side effects of Buprenorphine in cats · Medicines most reported with injection site reaction