Injection site reaction after Dexmedetomidine (Dexdomitor) in cats

52 reports to the FDA describe injection site reaction in cats given Dexmedetomidine. That is 2.0% of all reports for this medicine, compared with 1.2% across reports for all cat medicines, so it is reported unusually often with this medicine.

52Reports

52%Marked serious

9.6%Recovered

9.6%Died or euthanised

7 daysTypical onset

How soon it started

Same day

7 22%

1–2 days

5 16%

3–7 days

6 19%

1–4 weeks

13 41%

Over a month

1 3.1%

How the animals did

Recovered

4 7.7%

Recovered with lasting effects

1 1.9%

Still unwell when reported

26 50%

Died

5 9.6%

Not known

16 31%

Problems reported at the same time

Abnormal radiograph finding

9 17%

Limb amputation

8 15%

Abnormal cytology

7 13%

6 12%

5 9.6%

5 9.6%

5 9.6%

5 9.6%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Dexmedetomidine sedation and pain relief (also an oral gel for noise anxiety).

Products with this ingredient include Dexdomitor, Sileo. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Dexmedetomidine cause injection site reaction in cats?: 52 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

Injection site reaction after Buprenorphine 84 reports · 1.5% of its reports

All reported side effects of Dexmedetomidine in cats · Medicines most reported with injection site reaction