Hyperphosphataemia after Buprenorphine in cats

80 reports to the FDA describe hyperphosphataemia in cats given Buprenorphine. That is 1.4% of all reports for this medicine, compared with 1.0% across reports for all cat medicines.

80Reports

85%Marked serious

7.5%Recovered

44%Died or euthanised

2 daysTypical onset

How soon it started

Same day

13 19%

1–2 days

32 46%

3–7 days

16 23%

1–4 weeks

6 8.6%

Over a month

3 4.3%

How the animals did

Recovered

6 7.5%

Still unwell when reported

32 40%

Died

9 11%

Euthanised

26 33%

Not known

7 8.8%

Problems reported at the same time

74 93%

54 68%

36 45%

35 44%

32 40%

23 29%

22 28%

20 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause hyperphosphataemia in cats?: 80 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

Hyperphosphataemia after Dexmedetomidine (Dexdomitor) 37 reports · 1.4% of its reports

All reported side effects of Buprenorphine in cats · Medicines most reported with hyperphosphataemia