Proteinuria after Bexagliflozin (Bexacat) in cats

The FDA has received 99 reports of proteinuria in cats after Bexagliflozin. That is 2.4% of all reports for this medicine, compared with 0.5% across reports for all cat medicines, so it is reported unusually often with this medicine.

99Reports

38%Marked serious

0.0%Recovered

11%Died or euthanised

58 daysTypical onset

How soon it started

Same day

7 8.2%

1–2 days

2 2.4%

3–7 days

8 9.4%

1–4 weeks

17 20%

Over a month

51 60%

How the animals did

Still unwell when reported

45 45%

Died

2 2.0%

Euthanised

9 9.1%

Not known

43 43%

Problems reported at the same time

65 66%

47 47%

37 37%

37 37%

33 33%

27 27%

25 25%

24 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bexagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Bexacat. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bexagliflozin cause proteinuria in cats?: 99 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 58 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proteinuria with similar medicines

Proteinuria after Velagliflozin (Senvelgo) 133 reports · 2.8% of its reports
Proteinuria after Insulin 36 reports · 1.0% of its reports

All reported side effects of Bexagliflozin in cats · Medicines most reported with proteinuria