Elevated lipase after Bexagliflozin (Bexacat) in cats

The FDA has received 41 reports of elevated lipase in cats after Bexagliflozin. That is 1.0% of all reports for this medicine, compared with 0.2% across reports for all cat medicines, so it is reported unusually often with this medicine.

41Reports

54%Marked serious

2.4%Recovered

12%Died or euthanised

21 daysTypical onset

How soon it started

Same day

1 2.9%

1–2 days

4 12%

3–7 days

4 12%

1–4 weeks

10 29%

Over a month

15 44%

How the animals did

Recovered

1 2.4%

Still unwell when reported

24 59%

Died

1 2.4%

Euthanised

4 9.8%

Not known

11 27%

Problems reported at the same time

26 63%

18 44%

18 44%

17 41%

14 34%

14 34%

13 32%

13 32%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bexagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Bexacat. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bexagliflozin cause elevated lipase in cats?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated lipase with similar medicines

Elevated lipase after Velagliflozin (Senvelgo) 42 reports · 0.9% of its reports
Elevated lipase after Insulin 22 reports · 0.6% of its reports

All reported side effects of Bexagliflozin in cats · Medicines most reported with elevated lipase