Elevated cholesterol (total) after Bexagliflozin (Bexacat) in cats

The FDA has received 134 reports of elevated cholesterol (total) in cats after Bexagliflozin. That is 3.3% of all reports for this medicine, compared with 0.4% across reports for all cat medicines, so it is reported unusually often with this medicine.

134Reports
37%Marked serious
2.2%Recovered
16%Died or euthanised
29 daysTypical onset
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How soon it started

Same day
7 6.4%
1–2 days
4 3.7%
3–7 days
22 20%
1–4 weeks
27 25%
Over a month
49 45%

How the animals did

Recovered
3 2.2%
Still unwell when reported
63 47%
Died
6 4.5%
Euthanised
16 12%
Not known
46 34%

Problems reported at the same time

Hyperglycaemia
70 52%
Ketosis
67 50%
Weight loss
55 41%
Loss of appetite
47 35%
Liver problems
46 34%
Glucosuria
42 31%
Kidney problems
38 28%
Lethargy
37 28%

Age of the animals

Under 1 year
0
1–3 years
3
4–7 years
18
8–11 years
67
12+ years
41

About this medicine

Bexagliflozin treats diabetes in cats (oral, an SGLT2 inhibitor).

Products with this ingredient include Bexacat. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bexagliflozin cause elevated cholesterol (total) in cats?
134 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 29 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated cholesterol (total) with similar medicines

All reported side effects of Bexagliflozin in cats · Medicines most reported with elevated cholesterol (total)