Behaviour change after Amoxicillin + Clavulanate (Clavamox) in cats

96 reports to the FDA describe behaviour change in cats given Amoxicillin + Clavulanate. That is 4.0% of all reports for this medicine, compared with 5.4% across reports for all cat medicines.

96Reports
42%Marked serious
17%Recovered
17%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
22 31%
1–2 days
14 20%
3–7 days
17 24%
1–4 weeks
10 14%
Over a month
8 11%

How the animals did

Recovered
16 17%
Still unwell when reported
31 32%
Died
10 10%
Euthanised
6 6.3%
Not known
33 34%

Problems reported at the same time

Age of the animals

Under 1 year
12
1–3 years
11
4–7 years
27
8–11 years
17
12+ years
27

About this medicine

Amoxicillin treats bacterial infections.

Products with this combination include Clavamox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Amoxicillin + Clavulanate cause behaviour change in cats?
96 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Amoxicillin + Clavulanate in cats · Medicines most reported with behaviour change