Pentobarbital + Phenytoin side effects in horses

125 reports sent to the FDA between 1996 and 2026 involve Pentobarbital + Phenytoin in horses. The most reported problems were seizures, potency, low, restlessness or agitation. 30% were marked serious, and where it was recorded, signs eased after stopping the medicine in 25% of cases.

125Reports
30%Marked serious
98%Only medicine involved
0.8%Recovered
93%Died or euthanised
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About this medicine

Type: medicine.

Most reported side effects

Seizures
9 7.2%
Potency, low
5 4.0%
Restlessness or agitation
5 4.0%
Drug administration error
5 4.0%
Breathing problems
4 3.2%
Unrelated death
4 3.2%
Injection site reaction
3 2.4%
Overdose
2 1.6%
Paddling
1 0.8%
Toxicity
1 0.8%
Collapse
1 0.8%
Recumbency
1 0.8%
Excitation
1 0.8%
Vocalising
1 0.8%
Decreased heart rate
1 0.8%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a horse still getting fleas or heartworm), not about a side effect.

How soon problems started

Same day
38 100%
1–2 days
0 0.0%
3–7 days
0 0.0%
1–4 weeks
0 0.0%
Over a month
0 0.0%

Time from the first dose to the first sign, where both dates were reported (38 reports).

How the animals did

Recovered
1 0.8%
Died
58 46%
Euthanised
58 46%
Not known
8 6.4%

Breeds named most often

Popular breeds appear more often because there are more of them.

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