Septic arthritis after Hyaluronate Sodium in horses

The FDA has received 23 reports of septic arthritis in horses after Hyaluronate Sodium. That is 5.5% of all reports for this medicine, compared with 0.2% across reports for all horse medicines, so it is reported unusually often with this medicine.

23Reports
8.7%Marked serious
4.3%Recovered
48%Died or euthanised
–Typical onset
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How the animals did

Recovered
1 4.3%
Still unwell when reported
2 8.7%
Died
7 30%
Euthanised
4 17%
Not known
9 39%

Problems reported at the same time

15 65%
11 48%
Synovial fluid, abnormal
4 17%
Intentional misuse
4 17%

Age of the animals

Under 1 year
0
1–3 years
0
4–7 years
5
8–11 years
7
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Hyaluronate Sodium cause septic arthritis in horses?
23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Hyaluronate Sodium in horses · Medicines most reported with septic arthritis