Lameness after Hyaluronate Sodium in horses

The FDA has received 131 reports of lameness in horses after Hyaluronate Sodium. That is 31% of all reports for this medicine, compared with 2.5% across reports for all horse medicines, so it is reported unusually often with this medicine.

131Reports

19%Marked serious

22%Recovered

11%Died or euthanised

7 daysTypical onset

How soon it started

Same day

6 12%

1–2 days

7 13%

3–7 days

17 33%

1–4 weeks

19 37%

Over a month

3 5.8%

How the animals did

Recovered

29 22%

Still unwell when reported

16 12%

Died

7 5.3%

Euthanised

7 5.3%

Not known

72 55%

Problems reported at the same time

Swelling

42 32%

Joint effusion

35 27%

Injection site reaction

25 19%

22 17%

21 16%

20 15%

15 11%

15 11%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Hyaluronate Sodium cause lameness in horses?: 131 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lameness with similar medicines

Lameness after Pergolide 54 reports · 4.4% of its reports
Lameness after Ceftiofur 23 reports · 1.9% of its reports
Lameness after Polysulfated Glycosaminoglycan 27 reports · 5.2% of its reports
Lameness after Triamcinolone 44 reports · 32% of its reports

All reported side effects of Hyaluronate Sodium in horses · Medicines most reported with lameness