Low platelet count after Trazodone in dogs

The FDA has received 30 reports of low platelet count in dogs after Trazodone. That is 1.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

30Reports

90%Marked serious

10%Recovered

37%Died or euthanised

92 daysTypical onset

How soon it started

Same day

1 4.3%

1–2 days

2 8.7%

3–7 days

1 4.3%

1–4 weeks

3 13%

Over a month

16 70%

How the animals did

Recovered

3 10%

Still unwell when reported

12 40%

Died

2 6.7%

Euthanised

9 30%

Not known

4 13%

Problems reported at the same time

13 43%

12 40%

12 40%

11 37%

11 37%

10 33%

10 33%

8 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause low platelet count in dogs?: 30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 92 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Low platelet count with similar medicines

Low platelet count after Gabapentin 115 reports · 1.3% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with low platelet count