Increased respiratory rate after Trazodone in dogs

28 reports to the FDA describe increased respiratory rate in dogs given Trazodone. That is 1.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

28Reports

89%Marked serious

14%Recovered

39%Died or euthanised

65 daysTypical onset

How soon it started

Same day

3 16%

1–2 days

3 16%

3–7 days

1 5.3%

1–4 weeks

2 11%

Over a month

10 53%

How the animals did

Recovered

4 14%

Still unwell when reported

8 29%

Died

3 11%

Euthanised

8 29%

Not known

5 18%

Problems reported at the same time

14 50%

14 50%

13 46%

13 46%

12 43%

11 39%

Abnormal ultrasound finding

9 32%

Hypoglycaemia

8 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Trazodone reduces anxiety and stress.

Questions owners ask

Can Trazodone cause increased respiratory rate in dogs?: 28 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 65 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Increased respiratory rate with similar medicines

Increased respiratory rate after Gabapentin 76 reports · 0.8% of its reports

All reported side effects of Trazodone in dogs · Medicines most reported with increased respiratory rate