Skin rash or irritation after Tramadol in dogs

The FDA has received 108 reports of skin rash or irritation in dogs after Tramadol. That is 2.9% of all reports for this medicine, compared with 1.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

108Reports

53%Marked serious

19%Recovered

18%Died or euthanised

9 daysTypical onset

How soon it started

Same day

9 11%

1–2 days

8 10%

3–7 days

17 22%

1–4 weeks

22 28%

Over a month

23 29%

How the animals did

Recovered

16 15%

Recovered with lasting effects

4 3.7%

Still unwell when reported

50 46%

Died

8 7.4%

Euthanised

11 10%

Not known

19 18%

Problems reported at the same time

27 25%

22 20%

22 20%

22 20%

21 19%

20 19%

20 19%

16 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause skin rash or irritation in dogs?: 108 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin rash or irritation with similar medicines

Skin rash or irritation after Melarsomine (Immiticide) 180 reports · 0.8% of its reports
Skin rash or irritation after Polysulfated Glycosaminoglycan 71 reports · 1.3% of its reports
Skin rash or irritation after Diphenhydramine 190 reports · 4.0% of its reports
Skin rash or irritation after Butorphanol 74 reports · 1.7% of its reports
Skin rash or irritation after Cefpodoxime 299 reports · 7.4% of its reports
Skin rash or irritation after Florfenicol + Mometasone + Terbinafine 66 reports · 1.9% of its reports
Skin rash or irritation after Desoxycorticosterone Pivalate 66 reports · 2.0% of its reports
Skin rash or irritation after Propofol 49 reports · 1.6% of its reports
Skin rash or irritation after Dirlotapide 41 reports · 1.5% of its reports
Skin rash or irritation after Isoflurane 36 reports · 1.3% of its reports

All reported side effects of Tramadol in dogs · Medicines most reported with skin rash or irritation