Incorrect route of drug administration after Tiletamine + Zolazepam in dogs

The FDA has received 29 reports of incorrect route of drug administration in dogs after Tiletamine + Zolazepam. That is 2.0% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

29Reports
24%Marked serious
59%Recovered
10%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
9 56%
1–2 days
1 6.3%
3–7 days
1 6.3%
1–4 weeks
2 13%
Over a month
3 19%

How the animals did

Recovered
17 59%
Still unwell when reported
3 10%
Euthanised
3 10%
Not known
6 21%

Problems reported at the same time

Lateral recumbency
3 10%
Drug administration error
2 6.9%
Involuntary defecation
1 3.4%
1 3.4%

Age of the animals

Under 1 year
2
1–3 years
2
4–7 years
2
8–11 years
2
12+ years
0

About this medicine

Type: medicine.

Questions owners ask

Can Tiletamine + Zolazepam cause incorrect route of drug administration in dogs?
29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Incorrect route of drug administration with similar medicines

All reported side effects of Tiletamine + Zolazepam in dogs · Medicines most reported with incorrect route of drug administration