Reddening of the skin after Tigilanol Tiglate in dogs

The FDA has received 34 reports of reddening of the skin in dogs after Tigilanol Tiglate. That is 1.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

34Reports

68%Marked serious

32%Recovered

2.9%Died or euthanised

1 daysTypical onset

How soon it started

Same day

10 30%

1–2 days

11 33%

3–7 days

5 15%

1–4 weeks

4 12%

Over a month

3 9.1%

How the animals did

Recovered

11 32%

Still unwell when reported

2 5.9%

Died

1 2.9%

Not known

20 59%

Problems reported at the same time

Injection site reaction

31 91%

Swelling

25 74%

Loss of appetite

13 38%

Pain

12 35%

Didn't work as expected

11 32%

Wound

11 32%

Swollen limb

9 26%

Vomiting

8 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Tigilanol Tiglate cause reddening of the skin in dogs?: 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Reddening of the skin with similar medicines

Reddening of the skin after Melarsomine (Immiticide) 49 reports · 0.2% of its reports
Reddening of the skin after Diphenhydramine 106 reports · 2.2% of its reports
Reddening of the skin after Butorphanol 40 reports · 0.9% of its reports
Reddening of the skin after Cefpodoxime 52 reports · 1.3% of its reports
Reddening of the skin after Propofol 21 reports · 0.7% of its reports
Reddening of the skin after Isoflurane 22 reports · 0.8% of its reports
Reddening of the skin after Cephalexin 25 reports · 0.9% of its reports
Reddening of the skin after Atipamezole 23 reports · 0.9% of its reports
Reddening of the skin after Famotidine 27 reports · 1.0% of its reports
Reddening of the skin after Ketoconazole 26 reports · 1.2% of its reports

All reported side effects of Tigilanol Tiglate in dogs · Medicines most reported with reddening of the skin