Bradycardia after Sevoflurane in dogs

The FDA has received 115 reports of bradycardia in dogs after Sevoflurane. That is 14% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

115Reports
23%Marked serious
24%Recovered
41%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
33 89%
1–2 days
2 5.4%
3–7 days
0 0.0%
1–4 weeks
1 2.7%
Over a month
1 2.7%

How the animals did

Recovered
28 24%
Still unwell when reported
4 3.5%
Died
47 41%
Not known
36 31%

Problems reported at the same time

44 38%
24 21%
Bradypnoea
8 7.0%
Blood and lymphatic system disorder
7 6.1%

Age of the animals

Under 1 year
25
1–3 years
29
4–7 years
29
8–11 years
10
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Sevoflurane cause bradycardia in dogs?
115 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Bradycardia with similar medicines

All reported side effects of Sevoflurane in dogs · Medicines most reported with bradycardia